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Drug ReportsErgoloid mesylates
Ergoloid mesylates
Ergoloid Mesylates (ergoloid mesylates) is an unknown pharmaceutical. Ergoloid mesylates was first approved as Hydergine on 1982-01-01.
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FDA approval date
EMA approval date
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Study first post date
Last update post date
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Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ergoloid mesylates
Tradename
Company
Number
Date
Products
HYDERGINENovartisN-009087 DISCN1982-01-01
2 products
HYDERGINENovartisN-017993 DISCN1982-01-01
2 products
HYDERGINENovartisN-018418 DISCN1982-01-01
1 products
HYDERGINE LCNovartisN-018706 DISCN1983-01-18
1 products
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FDA
EMA
Brand Name
Status
Last Update
ergoloid mesylatesANDA2016-08-04
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C04: Peripheral vasodilators
— C04A: Peripheral vasodilators
— C04AE: Ergot alkaloid peripheral vasodilators
— C04AE01: Ergoloid mesylates
— C04AE51: Ergoloid mesylates, combinations
HCPCS
No data
Clinical
Clinical Trials
23 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Migraine disordersD008881EFO_0003821G434161113
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Migraine without auraD020326EFO_0005296G43.02—3——5
Migraine with auraD020325EFO_0005295G43.12—3——5
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———51———5
Renal insufficiencyD051437HP_0000083N1911———1
Vascular dementiaD015140—F01—1———1
Fragile x syndromeD005600—Q99.2—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289——————11
Squamous cell neoplasmsD018307——————11
Adenocarcinoma of lungD000077192——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameErgoloid mesylates
INN—
Description
Ergoloid mesylates (USAN), co-dergocrine mesilate (BAN) or dihydroergotoxine mesylate, trade name Hydergine, is a mixture of the methanesulfonate salts of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine).
Classification
Unknown
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C[C@@H]4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12.CC(C)[C@@]1(NC(=O)[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](Cc3ccccc3)N2C1=O.CC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C[C@@H]4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12.CCC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C[C@@H]4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12.CS(=O)(=O)O.CS(=O)(=O)O.CS(=O)(=O)O.CS(=O)(=O)O
Identifiers
PDB—
CAS-ID8067-24-1
RxCUI—
ChEMBL IDCHEMBL2311030
ChEBI ID—
PubChem CID87068835
DrugBankDB01049
UNII ID—
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
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Estimated US medical usage
Ergoloid mesylates
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 362 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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189 adverse events reported
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